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Home > BRANDS > ISATORI > ISATORI META-CEL, 30 SERVINGS

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Product Description : With the introduction of Meta-CEL, an entirely new frontier has been established in creatine/muscle-building supplement technology. Meta-CEL contains a unique, proprietary blend of two revolutionary complexes blended in exact scientific amounts to bring you the most advanced muscle-building formula ever developed. Quite simply Meta-CEL attempts to gather the new era of creatine transport science, derived from human, animal, and in vitro (test tube) investigations. Here's a look at what's in it and the science behind each ingredient.   Creatine Monohydrate To date, no other forms of creatine, e.g. creatine citrate, creatine pyruvate, creatine-magnesium complex, have convincingly shown superior real-world results in comparison to creatine monohydrate. Moreover, these "designer" forms of creatine cost more. One of the most thoroughly tested dietary supplements overall, and perhaps the most exhaustively tested sports nutrition ingredient outside of carbohydrates, is creatine monohydrate. Until several studies show that a different form of creatine is superior to creatine monohydrate when it is directly compared to creatine monohydrate, and that "superiority" is defined by significantly greater increases in fat-free mass and/or muscular performance, the jury rests. There is no compelling reason, scientific or rational, to use a different form of creatine than the monohydrate. Period. All other forms of creatine may be considered ineffective until proven effective and superior to creatine monohydrate.   Inzitol (D-Pinitol) This cousin of the nutrient inositol was first characterized in sugar pine trees. It is classified as a cyclitol, a sugar derivative that serves to protect plants from harsh environmental conditions. It is also present in soy meal, at a concentration of about 1% by weight, and is abundant in citrus fruits and legumes. Animal and muscle cell studies with D-pinitol have shown it to have insulin-mimicking effects, suggesting that it exerts the same actions as insulin independent of the presence of insulin. However, human studies in subjects with insulin resistance have yet to show a positive effect on insulin sensitivity.   Pushing Creatine Gains Even Further... If we were to peer into the muscle cell membrane, we would see what resembles a Saturday night at an exclusive dance club/bar. Inside the building is where all the action is taking place, but what's making the action happen are the VIP's gaining entry into the club. Creatine is a VIP during the loading stage, and when a creatine transporter "sees" creatine in the crowd, the revolving door is opened and creatine is ushered inside (much to the dismay of the others anxiously waiting in line). Creatine transporters are a series of closely related proteins that weave in and out of muscle, intestinal, and brain cell membranes. When they are abundant and in contact with the "outside" world, namely the world of chemicals floating in the blood, they can be stimulated by various agents. Welcome insulin and beta-adrenergic receptors.   Potentin Compound Synephrine and other phenolamines present in Citrus species extracts (e.g., Citrus aurantium) have been advocated as thermogenic, appetite-reducing, and body-composition-altering agents. The phenolamine synephrine is a "fraternal" chemical twin of the naturally occurring neurochemical epinephrine (a.k.a. adrenaline), but does not appear to share the same trait of causing a "fight or flight" experience, at least in relation to blood pressure elevation. The rationale behind the use of Citrus-derived synephrine and other phenolamines is that they are weak stimulators of alpha- and beta-adrenergic receptors. These are the same cellular receptors (from a variety of tissues) that are stimulated by ephedrine. To date, the only Citrus-derived phenolamine shown to stimulate human beta-adrenergic receptors appears to be syn

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